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heterozygous

C2
Uncommon

Pronunciation

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    • /ˌhɛtərəˈzaɪɡəs/

    Meanings

    Adjective

    1. having two different alleles at a genetic locus

    Beyond the definition

    Imagine you're building with LEGO bricks. If you only have red bricks, your creation is "homozygous"—everything is the same. But if you mix in some blue bricks, it becomes "heterozygous" because it now contains both red and blue. In biology, this idea applies to DNA. A heterozygous individual has inherited two different versions of a particular gene, called alleles, one from each parent. This means they carry two different sets of instructions for the same trait.

    For example, if one parent passes down an allele for brown eyes and the other passes down one for blue eyes, the child is heterozygous for that gene. They carry both versions, and the trait they actually show may depend on which allele is dominant. This term often appears in discussions of genetics, inheritance, and breeding.

    Examples

    1. 1

      Genetic trait

      The test showed that she is heterozygous for a gene linked to red hair.

    2. 2

      Carrier status

      Because he is heterozygous for the mutation, he carries it without having the disease himself.

    3. 3

      Plant breeding

      In this cross, about half of the plants are expected to be heterozygous.

    See also

    Similar

    • heterozygotic

    Shades of meaning

    Contrast

    • homozygous
    • hemizygous

    Used with (collocations)

    • heterozygous for
    • heterozygous genotype
    • heterozygous carrier
    • compound heterozygous

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    Forms and spellings

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    Main spelling

    • heterozygousadjective