heterozygote
C2Pronunciation
UK
- /hˈɛtrəzˌɪɡəʊt/
US
- /hˈɛtərˌoʊzɪɡˌoʊt/
Description
- An organism with two different alleles
- Two different versions of one gene
- Different gene forms from each parent
- Genetic carrier in some cases
- Not genetically identical at that gene
Imagine a gene as coming in two copies, one from each parent. When those two copies are different, the organism is called a heterozygote. In genetics, this means it has two different versions, called alleles, of the same gene.
This is common in plants, animals, and humans. For example, someone might get one version of a gene from one parent and a different version from the other. One version may shape the visible trait more strongly, but both are still part of the person's genetic makeup. This helps explain how traits are passed on and why living things show so much variety.
The term "heterozygote" is rooted in genetics, the study of how traits are passed through generations. It describes an individual organism that possesses two different alleles—variations of a gene—at a specific location (locus) on their chromosomes. If you think of genes as the master manual for building an organism, alleles are like slightly different versions of the same chapter.
To visualize this, consider the pea plants famously studied by Gregor Mendel. If "T" represents the allele for tallness and "t" represents the allele for shortness, a plant with two "T" alleles (TT) is a homozygote, meaning it is "true-breeding" for tallness. A plant with two "t" alleles (tt) is also a homozygote, but for shortness. However, a plant with one "T" and one "t" allele (Tt) is a heterozygote.
In this pairing, the "T" allele is dominant, meaning the heterozygote plant will appear tall even though it carries the instruction for shortness. The recessive trait (shortness) remains hidden in the individual's appearance (phenotype) but remains part of its genetic makeup (genotype). This allows the organism to act as a "carrier," potentially passing the hidden trait on to future generations.
The concept of heterozygosity is also crucial for understanding health. Many genetic conditions are only expressed if an individual is a homozygote for a specific disease-causing allele. Heterozygotes, possessing only one copy of that allele, often remain perfectly healthy themselves while acting as carriers. Ultimately, "heterozygote" signifies the genetic "difference" that contributes to the incredible biological variety we see across the planet, serving as a cornerstone for evolution and inheritance.
Examples
- 1
Plant genetics
In pea plants, a heterozygote may have one gene for purple flowers and one for white flowers.
- 2
Medical genetics
She is a heterozygote for the sickle-cell gene, so the doctor explained what that could mean for her children.
- 3
Genetic crosses
When two heterozygotes are crossed, some of the offspring may show the recessive trait.
Domain
in genetics, crossed
bred together
Forms and spellings
1 form open this card.
Main spelling
- heterozygotenoun