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heterozygosity

C2
noun

Pronunciation

UK

  • /hˌɛtrəʊzɪɡˈɒsɪtɪ/

US

  • /hˌɛtərˌoʊzɪɡˈɔsɪti/

Description

Imagine building with LEGO bricks. If you only have one type of brick, your creations are limited. Heterozygosity is like having a mix of different colored and shaped bricks. It means there are two different versions (called alleles) of a gene at the same place in a pair of chromosomes. Think about eye color: maybe one parent passes on a version linked to blue eyes and the other passes on a version linked to brown eyes. When the two versions are different, that gene shows heterozygosity.

This is not just about eye color; it can apply to many genes. In a whole population, high heterozygosity often points to more genetic variety, which can help a species adjust to change. Scientists who study endangered animals pay close attention to it, because low levels can be a warning sign of inbreeding or poor genetic health.

Examples

  1. 1

    Genetic diversity

    The researchers found high heterozygosity in the wild population, which suggested strong genetic diversity.

  2. 2

    Inbreeding

    Breeding too closely within a small group can reduce heterozygosity over time.

  3. 3

    Tumor genetics

    The pathologist looked for loss of heterozygosity in the tumor sample.

    • Domain

      loss of heterozygosity

      a genetic change where one of two different gene versions is lost

Forms and spellings

1 form open this card.

Main spelling

  • heterozygositynoun