mutational
C2Pronunciation
UK
- /mjuːtˈeɪʃənəl/
US
- /mjuːtˈeɪʃənəl/
Description
- related to genetic change
- caused by mutation
- involving DNA changes
The word "mutational" describes anything connected to mutations, which are changes in genetic material such as DNA or RNA. Think of it as a word for something caused by or related to those changes. It is used most often in biology and genetics when people talk about evolution, disease, or differences between living things. A change of this kind is not always harmful; some are neutral, and some can even help an organism survive. Imagine a scientist tracking how a virus changed over time: they might study its mutational pattern to understand how it spread.
"Mutational" is an adjective that refers to anything pertaining to or caused by a mutation. A mutation, in its simplest form, is a change in the genetic material of an organism—its DNA or RNA. These changes can occur spontaneously due to errors during cell division, or they can be induced by external factors like radiation or certain chemicals.
While often associated with negative consequences like genetic diseases (think cystic fibrosis or sickle cell anemia), mutations are also a driving force behind evolution. Beneficial mutational changes can help species adapt to their environments over time. Scientists studying cancer frequently investigate mutational patterns in tumor cells to understand how the disease develops and spreads, looking for specific mutational signatures that might suggest a particular treatment approach.
The term "mutational" isn't typically used in everyday conversation; it's mostly confined to scientific contexts such as genetics, biology, virology, and evolutionary studies. You might read about "mutational analysis" in a research paper or hear scientists discuss the "mutational load" of a population. It emphasizes that something is resulting from or connected to changes at the genetic level. So, if you encounter "mutational" in a text, you are probably stepping into the world of genetics and seeing how living things change over time.
Examples
- 1
Research samples
Researchers compared the mutational changes in the samples before and after treatment.
- 2
Targeted therapy
The tumor's mutational profile helped doctors choose a more targeted therapy.
Domain
mutational profile
the set of genetic changes found in a cell, tumor, or organism
- 3
Immunotherapy
Some cancers have a high mutational burden and may respond better to immunotherapy.
Domain
mutational burden
the number of genetic changes in a cancer sample
- 4
Tobacco exposure
The team found a mutational signature linked to long-term tobacco smoke exposure.
Domain
mutational signature
a pattern of genetic changes that can point to a cause
Forms and spellings
1 form open this card.
Main spelling
- mutationaladjective