indomethacin
C2Pronunciation
UK
- /ˌɪn.dəʊˈmɛθ.əs.ɪn/alt-ofalternativeuncountablenoun
US
- /ˌɪn.doʊˈmɛθ.əs.ɪn/alt-ofalternativeuncountablenoun
Description
- prescription pain reliever
- anti-inflammatory medicine
- NSAID
- arthritis treatment
Imagine your joints are throwing a noisy party: swollen, sore, and hard to move. This medicine helps calm that trouble by lowering inflammation and easing pain. You can think of it as a strong helper that tells the body to quiet down.
You would not usually take it for a simple headache. Doctors prescribe it for problems such as arthritis, gout, and some kinds of inflammation. It works by blocking body chemicals that lead to pain and swelling. You usually need a prescription for it because it can cause side effects and should be used with medical care. In some cases, it is also used in hospitals for certain conditions in premature babies.
Indomethacin is a nonsteroidal anti-inflammatory drug, or NSAID. It is used to reduce pain, swelling, and stiffness caused by inflammation. It is not as well known as ibuprofen or aspirin, but it is an important prescription medicine for some painful inflammatory conditions.
Doctors often prescribe it for osteoarthritis, rheumatoid arthritis, gout, and ankylosing spondylitis. It may also be used for some kinds of bursitis, tendonitis, or eye inflammation, depending on the patient and the form of the medicine.
Rather than only dulling pain, it helps by lowering the inflammation that is causing the pain. It does this by blocking cyclooxygenase enzymes, often called COX enzymes. These enzymes help the body make prostaglandins, which are chemicals involved in pain and swelling. Because this medicine can be strong, it can also cause side effects such as stomach upset, ulcers, bleeding, kidney problems, or increased heart risks in some people. That is why doctors use it with care, especially if a patient has other health problems or takes other medicines.
It also has some specialized medical uses. For example, in neonatal care it may be used to help close a patent ductus arteriosus, an opening in the heart circulation that sometimes remains open in premature babies. So while you are unlikely to see it as an everyday household medicine, it remains a valuable treatment for people dealing with serious inflammation and pain.
Examples
- 1
Gout treatment
The doctor prescribed indomethacin for his gout flare.
- 2
Taking medicine
Take indomethacin with food if it upsets your stomach.
- 3
Treatment progress
After two days on indomethacin, the swelling in her ankle started to go down.
Pattern
on + medicine
taking that medicine
Forms and spellings
1 form open this card.
Main spelling
- indomethacinnoun