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conformation

B2
Uncommon

Pronunciation

UK

  • /kɒnfɔːmˈeɪʃən/

US

    Meanings

    Noun

    1. the shape, structure, or arrangement of something's parts

    2. the three-dimensional arrangement of atoms or biological molecules

    3. an animal's physical build as judged against breed standards

    Beyond the definition

    Conformation describes the way something is shaped or arranged—think of it as its overall physical form. It's more than just what something is made of; it's about how those parts come together to create a specific silhouette or structure. A sculptor might carefully consider the conformation of a statue to convey strength or grace. In biology and animal husbandry, conformation refers to the physical build of an organism. For example, you might say a horse has excellent "conformation" if its bone structure and muscle placement perfectly meet the standards for its breed.

    Think of building with LEGO bricks: you can use the exact same pieces (the materials), but arrange them in different ways to create very different results—a house, a car, or a spaceship!

    Examples

    1. 1

      Molecular shape

      Heat can change the conformation of a protein and stop it from working properly.

      • Domain

        In biology and chemistry, conformation means the way a molecule is arranged in space.

    2. 2

      Protein activity

      The drug binds to the receptor and stabilizes its active conformation.

    3. 3

      Animal breeding

      The breeder liked the young horse's conformation, especially its strong back and straight legs.

      • Domain

        In animal breeding, conformation means the shape and proportions of an animal's body.

    See also

    Similar

    Shades of meaning

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    Do not confuse

    Used with (collocations)

    • molecular conformation
    • protein conformation
    • body conformation

    Word family

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    Forms and spellings

    2 forms open this card.

    Main spelling

    • conformationnoun

    Forms

    • conformationspluralnoun