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conformation

B2
noun

Pronunciation

UK

  • /kɒnfɔːmˈeɪʃən/

US

  • /kɑːnfɔːrmˈeɪʃən/

Description

Conformation describes the way something is shaped or arranged—think of it as its overall physical form. It's more than just what something is made of; it's about how those parts come together to create a specific silhouette or structure. A sculptor might carefully consider the conformation of a statue to convey strength or grace. In biology and animal husbandry, conformation refers to the physical build of an organism. For example, you might say a horse has excellent "conformation" if its bone structure and muscle placement perfectly meet the standards for its breed.

Think of building with LEGO bricks: you can use the exact same pieces (the materials), but arrange them in different ways to create very different results—a house, a car, or a spaceship!

Examples

  1. 1

    Molecular shape

    Heat can change the conformation of a protein and stop it from working properly.

    • Domain

      In biology and chemistry, conformation means the way a molecule is arranged in space.

  2. 2

    Protein activity

    The drug binds to the receptor and stabilizes its active conformation.

    • Meaning

      active conformation

      the shape a protein has when it is working

  3. 3

    Animal breeding

    The breeder liked the young horse's conformation, especially its strong back and straight legs.

    • Domain

      In animal breeding, conformation means the shape and proportions of an animal's body.

Forms and spellings

2 forms open this card.

Main spelling

  • conformationnoun

Forms

  • conformationspluralnoun