WordGarden.iopyrimidine
C2Pronunciation
UK
US
Meanings
Noun
a nitrogen-containing compound class that includes cytosine, thymine, and uracil
Beyond the definition
Imagine the blueprints for life: that's DNA and RNA. Inside those blueprints are small parts called bases. A pyrimidine is a kind of ring-shaped compound with nitrogen, and the word is often used for a group of bases that includes cytosine, thymine, and uracil. These bases help carry genetic information, a bit like letters in the alphabet of life. You'll mostly see this term in genetics, chemistry, biology, or medicine.
Pyrimidine is an organic compound with an important role in biology. In chemistry, it is a six-membered ring with two nitrogen atoms. In biology, the word is also used for a family of nitrogen-containing bases built on that ring. But the most important thing to understand is what it does.
Pyrimidines are one of the two main classes of bases found in DNA and RNA, the other being purines. The three main pyrimidine bases are cytosine (C), thymine (T, found mainly in DNA), and uracil (U, found mainly in RNA). These bases are vital parts of genetic material. In DNA, cytosine pairs with guanine, and thymine pairs with adenine, helping form the double-helix structure associated with DNA.
Beyond genetics, pyrimidine-related compounds also appear in some vitamins and take part in many processes inside living things. In medicine, understanding pyrimidine metabolism matters because some drugs block pyrimidine synthesis to slow the growth of fast-dividing cells, including cancer cells.
So, while you may not hear the word "pyrimidine" in everyday conversation, it sits quietly behind some of the most basic parts of life, from genetic information to key chemical reactions in the body. It's a small structure with a huge impact.
Examples
- 1
Biology class
In biology class, we learned that cytosine and thymine are pyrimidines.
- Grammar
pyrimidines is often used in the plural for this group of bases
- 2
Cell growth
The researchers found a defect in pyrimidine synthesis, which slowed cell growth.
- 3
Antiviral drugs
Some antiviral drugs are pyrimidine analogs that block the virus from copying its genetic material.
See also
Similar
- 1,3-diazine
Shades of meaning
- pyrimidine base
Contrast
- purine
- pyridine
Used with (collocations)
- pyrimidine ring
- pyrimidine synthesis
- purines and pyrimidines
Word family
- pyrimidinic
Explore
- heterocycle
- nucleobase
Forms and spellings
1 form open this card.
Main spelling
- pyrimidinenoun