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neurotoxicity

C2
Uncommon

Pronunciation

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      Meanings

      Noun

      1. toxic damage or harmful effects on the nervous system caused by a substance or exposure

      Beyond the definition

      Imagine your body's electrical wiring: that's a lot like your nervous system. Neurotoxicity happens when something harms those wires and interrupts the way signals travel. It can be caused by certain chemicals or other toxic substances, and it may lead to problems with thinking, feeling, moving, or staying healthy. You might hear about neurotoxicity when people talk about pollution, workplace exposure, or side effects from some medicines. Lead poisoning is a classic example.

      It isn't always immediate; sometimes the damage builds up over time. It can affect different parts of the nervous system, from the brain and spinal cord to the nerves in your hands and feet. A character in a detective novel might suffer from slow-onset neurotoxicity after years of working with dangerous chemicals.

      Examples

      1. 1

        Chemotherapy risk

        Some chemotherapy drugs can cause neurotoxicity, so doctors watch for numbness or tingling.

      2. 2

        Research findings

        The study found no evidence of neurotoxicity at the lower dose.

      3. 3

        Patient monitoring

        Patients taking this medicine should be monitored for signs of neurotoxicity.

        • Patternmonitor someone for signs of + condition

          watch carefully to see if it appears

      4. 4

        Drug interaction

        The risk of neurotoxicity increases when the two drugs are used together.

      More examples
      1. 5

        Laboratory exposure

        Long-term exposure to the solvent has been linked to neurotoxicity in laboratory animals.

        • Patternbe linked to + effect

          be connected with it, but not always proven to cause it

      See also

      Similar

      • nerve toxicity
      • neurotoxic injury

      Shades of meaning

      • neurotoxic effect
      • toxic encephalopathy

      Contrast

      • neuroprotection

      Used with (collocations)

      • cause neurotoxicity
      • drug-induced neurotoxicity
      • signs of neurotoxicity
      • neurotoxicity testing

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      Forms and spellings

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      Main spelling

      • neurotoxicitynoun