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elution

C2
Uncommon

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      Meanings

      Noun

      1. the washing of a substance out of a material, especially in chromatography

      Beyond the definition

      Imagine you're making tea. Hot water passes through the leaves and carries the flavor and color away with it. In science, elution works in a similar way: a liquid, and sometimes a gas, moves through a material and carries a substance out of it. This is often used in lab work to separate and collect different parts of a mixture.

      You will most often see this in chemistry, biology, and especially chromatography, a method for testing or purifying substances. If a scientist says they are doing an "elution step," they mean they are washing a wanted substance off a material so it can be collected.

      Examples

      1. 1

        DNA extraction

        The DNA was collected during elution, after the washing steps were finished.

      2. 2

        Chromatography method

        The lab switched to gradient elution to separate the two compounds more clearly.

        • Domaingradient elution

          elution where the liquid conditions change step by step

      3. 3

        Troubleshooting

        Poor elution left part of the sample in the column, so the team adjusted the solvent.

      See also

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      Shades of meaning

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      Used with (collocations)

      • elution buffer
      • elution profile
      • gradient elution
      • isocratic elution

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      Forms and spellings

      1 form open this card.

      Main spelling

      • elutionnoun