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centrosomal

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Pronunciation

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      Meanings

      Adjective

      1. relating to a centrosome in a cell

      Beyond the definition

      Imagine your cells are tiny cities constantly building and rebuilding. The centrosome is like the city's central planning department, organizing the roads (microtubules) needed for everything from transporting materials to dividing the city into two identical halves. Anything centrosomal relates to this crucial organelle or its functions. Scientists studying cell division often focus on centrosomal activity because it is key to healthy growth and to preventing errors that can lead to diseases like cancer. You might hear about "centrosomal amplification" in cancer cells, meaning they have too many of these organizing centers, which can contribute to uncontrolled division.

      Examples

      1. 1

        Cell division

        The study identified a centrosomal protein that is active during cell division.

      2. 2

        Mutant cells

        In the mutant cells, centrosomal duplication started too early.

      3. 3

        Chromosome separation

        Loss of the gene disrupted centrosomal organization and caused errors in chromosome separation.

      See also

      Similar

      • centrosome-associated
      • centrosome-related

      Shades of meaning

      • pericentrosomal

      Contrast

      • non-centrosomal
      • centriolar

      Do not confuse

      Used with (collocations)

      • centrosomal proteins
      • centrosomal localization
      • centrosomal defects
      • centrosomal microtubule nucleation

      Word family

      Explore

      • microtubule-organizing center
      • spindle pole

      Forms and spellings

      1 form open this card.

      Main spelling

      • centrosomal